Transpharmation Logo
  • Contact Us

Models & Assays

Disease Model EfficacyPK & SafetyAged Beagle Model

Pathology

  • Aged Dogs Exhibit Both Early Amyloid-Aβ and Tau Pathologies

Drug Screening

  • Aβ Antibody Strategies
  • BACE Inhibitors
  • Comparative Drug Screening

Imaging

  • Cancer Imaging
  • Functional Brain Imaging
  • Image Processing
  • Interventional Imaging
  • Magnetic Resonance Spectroscopy
  • Musculoskeletal Imaging
  • Quantitative Magnetic Resonance
  • Specific Organ Imaging
  • Structural Brain Imaging
  • Whole Body Imaging

Functional Brain Imaging

  • Dynamic contrast perfusion to assess blood brain barrier permeability and regional cerebral blood flow using either MRI or CT
  • PET/CT imaging with additional coregistration to MRI images if required to quantify glucose uptake
  • Imaging of brain tissues using standard PET radiopharmaceuticals eg F-18 DOPA
  • Imaging of brain tissues with custom developed radiopharmaceuticals linked to specific naturally occurring brain chemicals or novel compounds
F-18 DOPA

Dynamic perfusion CT (A) Dynamic perfusion CT (B)

Dynamic perfusion CT images of a dog brain with cerebral blood flow (CBF) maps demonstrating an increase in CBF when end tidal CO2 is increased from 35mmHg (A) to 68mm Hg(B).

Company

  • Our Team
  • Publications
  • News
  • Careers
  • Animal Welfare
  • Privacy Policy
  • Accessibility Policy
  • Cookies Policy

Services

  • Alzheimer's Disease
  • Bioanalytical Studies
  • CNS Drug Disposition
  • Cognitive Assessment
  • Depression/Anxiety
  • EEG
  • Epilepsy
  • Essential Tremor
  • Imaging
  • Inflammatory Pain
  • Inflammation
  • Medical Cannabis
  • Migraine
  • Molecular Biomarkers
  • Multiple Sclerosis
  • Neuropathic Pain
  • Operant Platform
  • Parkinson's Disease
  • PK/PD Studies
  • PK-Bridge
  • Psychedelics
  • PXB Mouse Studies
  • Safety Studies
  • Schizophrenia
  • Veterinary Research
North America
1-548-538-2371
Europe
+44 (0)130 440 3165
Contact us

© 2024 Transpharmation™. All Rights Reserved.
Sitemap
LinkedIn account
Youtube account