For over a decade, Transpharmation has been providing research and development services in the companion animal market. Our scientists and veterinarians are leading experts in the field of cognition and general behaviour, anxiety, aging, and life-span development.

Our colony encompasses a wide variety of companion animal populations, including both general research cohorts and disease-specific groups with naturally occurring conditions such as osteoarthritis, mitral valve disease, periodontal disease, atopic dermatitis and other age-associated disorders. In addition, we offer induced disease models, including type I diabetes, obesity, and gut dysbiosis, providing versatile and clinically relevant platforms to support therapeutic development across multiple indications.

Leading veterinary medicine developers trust us to help guide and conduct innovative research studies and early proof-of-concept evaluations that provide evidence to support product claims and regulatory submissions.

Our goal is to help evaluate and develop innovative products which improve the quality of life of companion dogs and cats. A summary of populations and example endpoints are summarized below.

Osteoarthritis

  • Modified canine brief pain inventory
  • T-maze
  • Actical® activity monitoring
  • Zeno™ walkway
  • Orthopedic examinations
  • Glasgow pain scoring
  • Radiographic imaging
  • Synovial fluid collection

Mitral Valve Disease

  • ECG
  • Echocardiogram
  • Blood pressure
  • Biomarker analysis

Periodontal Disease

  • Gingival pocket depth measurements
  • Dental examinations
  • Radiographic evaluation
  • Saliva, CGF, plaque sampling

Induced Type I Diabetes

  • Blood glucose measurement
  • Continuous interstitial fluid glucose measurement
  • IVGTT and insulin sensitivity
  • Serum lipid profile and fructosamine

Atopic Dermatitis

  • Pruritic behaviour activity scoring
  • CADESI scoring
  • Skin photographs
  • Inflammatory biomarkers

Obesity

  • Body weight and body condition scoring
  • Food intake
  • QMR, DEXA or MRI
  • IVGTT and insulin sensitivity

Gut Microbiome & Dysbiosis

  • Fecal sampling
  • Fecal scoring
  • Biomarker analysis