40 Hz Auditory Steady-State Response (ASSR)

The auditory steady-state response, or ASSR, is an EEG response evoked by 40 Hz tones which, in healthy people, synchronizes neuronal activity across wide areas of the neocortex. The 40 Hz ASSR reflects the integrity of cortical networks involved in auditory processing, and is actively used in both clinical and preclinical schizophrenia research.

Readouts include:

• ASSR response amplitude (average and pharmacodynamic readouts)
• Reversal of induced deficits in ASSR
• Genetic model phenotyping
• Simultaneous estimation of qEEG effects