Anxiety
Anxiety is one of the most common behavioral conditions affecting companion animals and can significantly impact welfare and quality of life. Transpharmation offers validated models of situational stress and anxiety that enables the evaluation of therapeutics, nutritional interventions, and behavioral health products using measurable behavioral and physiological endpoints. Our translational approach provides objective data to support confidence in decision-making throughout the development process.
Detail of offering
Transpharmation has extensive experience evaluating situational fear, anxiety, and stress in companion animals using standardized behavioral models. These models generate consistent and measurable responses that support the assessment of intervention efficacy and biological activity.
Our noise-induced model uses a controlled sound stimulus such as thunder to induce measurable stress-related responses. Assessments may include:
- Behavioral observations and global anxiety scoring
- Activity monitoring
- Heart rate measurements
- Cortisol assessment
- Scanning and vigilance behaviors
The model provides a reproducible platform for evaluating interventions targeting situational stress and anxiety.
Our transportation model assesses stress responses during vehicle travel, providing a clinically relevant measure of situational stress. Endpoints may include:
- Global anxiety scoring
- Lip-licking and other behavioral indicators
- Heart rate monitoring
- Cortisol assessment
- Body position and activity measurements
This model supports the evaluation of therapies intended to reduce travel-related anxiety and stress responses.
Studies can incorporate behavioral observations together with physiological biomarkers to provide a comprehensive assessment of treatment response. Common measures include cortisol, heart rate, activity monitoring, and validated behavioral scoring systems.
Platforms used
Electroencephalography (EEG) In-vivo rodent telemetry
Imaging Services Companion animal imaging
Operant Platform Motivation, impulsivity, attention, cognition, memory
PK/PD Studies Endpoints for lead optimization
PK-Bridge PK studies for discovery budgets
Cognitive Assessment Aged-dog memory and cognitive decline
Have a program in mind?
Whether you are developing a pharmaceutical, nutritional, or behavioral health solution, our companion anxiety models can provide translational data to support your program. Contact our team to discuss your research objectives and study design requirements.