Models & Assays
Cancer Imaging
Several imaging protocols can be used to quantify the efficacy of new therapeutics. These can be conventional anatomic measures of tumor size using MRI, ultrasound or radiographs. Other functional measures that can be used on a quantitative basis pre and post treatment as a measure of the therapeutic effect of a new agent include:
- FDG PET imaging of glucose metabolism in tumors. Reduced glucose metabolism is a measure of therapeutic success.
- Dynamic contrast enhanced MRI to quantify effect of agents on angiogenesis. Reduced angiogenesis is a measure of therapeutic success