Models & Assays
Novel Object Recognition Test
This test of recognition memory is based on the tendency of rodents to preferentially explore a novel compared to a familiar object. Test subjects are exposed to a sample stimulus (object), and after a delay of minutes to hours, are presented with the sample object together with a novel object. Memory of the familiar object is gauged by a time difference score spent exploring each object.
Validation Data: Age-dependent impairment in learning and memory assessed by the novel object recognition task.
Aged rats show a decline in novel object recognition at 3h post sample stage, unlike young controls. Both young and aged rats show decline at 24h post sample stage.