Inflammation Biomarkers

Reliable characterization of inflammatory pathways is critical for understanding disease progression and therapeutic efficacy. We offer flexible biomarker solutions that enable comprehensive monitoring of cytokine responses and inflammatory signaling across diverse preclinical studies.

Rat LPS-induced inflammation model

Bar chart of plasma TNF-α (pg/mL) after LPS with vehicle, five doses of roflumilast, or dexamethasone: TNF-α falls with roflumilast and with dexamethasone.

LPS stimulated substantial generation of TNF-α in the plasma with roflumilast and dexamethasone attenuating LPS-induced elevations in plasma.

Key biomarker panels

  • IL-1β
  • IL-2
  • IL-6
  • IL-10
  • IL-17A/F
  • TNF-α
  • IFN-γ
  • MCP-1 (CCL2)
  • KC/GRO (CXCL1)
  • MIG (CXCL9)
  • IP-10 (CXCL10)
  • MIP-1α (CCL3)
  • MIP-1β (CCL4)
  • CRP
  • Corticosterone