
News and Conferences
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New published work!
Coinciding with World Diabetes Day, 14th November, is the publication of our work, ‘Induction of Type I Diabetes Mellitus in Beagle Dogs Using Alloxan and Streptozotocin’. Important insight that takes us nearer to enhanced translatability to the human health field. -
Name change announcement, news from the CEO
It has now been just over a year since InterVivo Solutions (headquartered in Toronto, Canada) acquired Transpharmation, (headquartered in London, UK) bringing together two Neuroscience-centric Contract Research Organisations (CROs). This has enabled us to deliver a wider set of capabilities, along with an even deeper knowledge base, to assist our clients in the Global Pharmaceutical, Animal Health and Biotech Sectors. -
CNS Therapeutic Xchange Europe 2022, Zurich - 24th November
Transpharmation's Scientific Lead for EEG, Sleep and Epilepsy, Sandor Kantor PhD, will be making a spotlight presentation on the 24th of November at 13.20-13.50. His presentation is titled 'The effect of CNS-acting drugs on rodent mismatch negativity is modulated by vigilance states' and will expand on the following aspects: Mismatch negativity (MMN) is a component of event-related potentials that is diminished in many neuropsychiatric disorders including schizophrenia; Central nervous system (CNS)-acting drugs often alter vigilance states, and it is not well understood how the drug-induced changes in sleep-wake behaviour affect MMN generation; An overview of the recent rodent MMN research with a special focus on vigilance state specific changes and discuss the methodological aspects and future implications of the latest findings.
For further information about this event please see here:
https://www.hub-xchange.com/cns-therapeutics-xchange-europe-2022/#anchor1
To view the presentation after the event please contact us.

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Society for Neuroscience 2022, November 12-16, California
This year’s prestigious event is taking place at the San Diego Convention Centre in San Diego, CA. We are looking forward to seeing familiar faces and meeting new ones. Covering a number of our translational services, we will have several posters on display, along with several members of our scientific team on hand to answer questions, hold meetings and update you on the latest developments that we are able to offer you. Keep an eye on our Linkedin profile for more details coming out soon.

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ECNP Congress, 15th-18th October - Vienna, Austria
The annual ECNP Congress is Europe’s premier scientific meeting for disease-oriented brain research, annually attracting more than 5,000 psychiatrists, neuroscientists, neurologists and psychologists from around the world. Transpharmation will be presenting two posters; (1) Differential effects of repeated treatment with DOI and psilocybin on the head-twitch response (HTR), locomotor activity and anxiety-like behaviour and (2) 2,5-Dimethoxy-4-iodoamphetamine (DOI) enhances motivation in low and medium but not high performers in the progressive ratio (PR) task in rats. We look forward to seeing you, but if you are unable to attend this event, we will make the posters available to you on our publications page after October 18th. For more details, please feel free to contact us.

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Here, there and everywhere - we love meeting up with you!
Digital conferences were a useful solution during the periods of lockdown, but there is nothing that quite replaces presenting the results of new studies and meeting with customers old and new in a face to face environment. -
Recent collaborative work published by Frontiers in Molecular Neuroscience
Frontiers in Molecular Neuroscience have recently published Transpharmation's collaborative research with Cindy Périer, Amy Fisher and Mikhail Kalinichev, exploring the efficacy of BoNT/A for inflammatory Pain in Mice. For over three decades, BoNT/A (botulinum neurotoxin Type A) has been used to treat muscle hyperactivity. Following studies in animals demonstrating inhibition of pain transmitters at peripheral and central levels, BoNTs have also been explored in a growing range of human pain conditions as potential analgesic agents. You can read it here: Frontiers in Molecular Neuroscience. For further information about this study or to enquire about booking in your work with us please contact us. -
HubXchange's US West Coast CNS Therapeutics Meeting - 29th September
With preclinical/clinical transition being the largest failure risk in CNS therapeutics development, Transpharmation will be revealing new scientific development work at the 2022 HubXchange’s CNS Therapeutics West Coast round table meeting, where senior drug developers from pharma and biotech share experiences and discuss the future research landscape. Chief Scientific Officer Guy Higgins, PhD, is a keynote speaker this year and will be presenting 'An application of a versatile rodent operant platform to drug discovery today.'
We will make this work available on our website if you are unable to attend.

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Animals in scientific research, 7th Annual Conference, by PolLASA. 12-14th September, Warsaw, Poland
This event will focus on neurobiology within the areas of psychiatry and psychology, behaviour, addiction models and neurodegenerative diseases. Transpharmation will be on hand to present a recent study; "Stress based animal models: refinement vs. translation". If you are not attending this conference, our work will be made available for you to see in our Publications page after the event.

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The Safety Pharmacology Society Annual Meeting - September 11-14, Montréal, Canada
The Safety Pharmacology Society (SPS) presents its Annual Meeting in partnership with the Canadian Society of Pharmacology and Therapeutics (CSPT). There's lots going on; find out more here https://web.cvent.com/event/7f5258b7-2dac-4efb-b6ff-6789cff237fe/summary. We will be at Booth 310 where we look forward to talking to you about our PK and safety pharmacology capabilities in rodents and dogs, and to discuss your study needs. See you there!

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