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Models & Assays

Disease Model EfficacyPK & SafetyAged Beagle Model

Pathology

  • Aged Dogs Exhibit Both Early Amyloid-Aβ and Tau Pathologies

Drug Screening

  • Aβ Antibody Strategies
  • BACE Inhibitors
  • Comparative Drug Screening

Imaging

  • Cancer Imaging
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  • Image Processing
  • Interventional Imaging
  • Magnetic Resonance Spectroscopy
  • Musculoskeletal Imaging
  • Quantitative Magnetic Resonance
  • Specific Organ Imaging
  • Structural Brain Imaging
  • Whole Body Imaging

Whole Body Imaging

Whole body imaging protocols are used for assessing the effects of therapeutics on metabolism and feeding behavior. Using dual energy x-ray absorptiometry (DEXA) body composition can be determined non invasively in longitudinal studies. These studies give body composition in terms of the percentage of fat, lean and bone tissue. Body composition is an important component in obesity studies.

DEXA of a dog and MR images

From left to right: DEXA image of a dog; MR Image of rat abdomen; MR image segmented into visceral (yellow) and subcutaneous (blue) fat.

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